Key points The novel IFNα-2b AOP2014 administered once every two weeks (or once a month) has low toxicity and induces high and sustained response rates in PV patients. AOP2014 induces significant partial and complete molecular response rates, as reflected by reduction of JAK2 allelic burden Click here for the complete article Details on the clinical trial […]
THE STORY OF JAK2 Four teams race to find the mysterious cause of a group of blood cancers. JAK2 MUTATIONS AT A GLANCE Involved in: blood cancers and disorders including polycythemia vera, primary myelofibrosis, thrombocythemia, leukemia. Testing requires: a blood draw. Bone marrow samples occasionally used. Prognosis: Patients with a JAK2 mutation have a lower […]
J Korean Med Sci. 2016 Oct;31(10):1579-1585. English. Published online Jul 22, 2016. http://dx.doi.org/10.3346/jkms.2016.31.10.1579 © 2016 The Korean Academy of Medical Sciences. Incidence, Survival and Prevalence Statistics of Classical Myeloproliferative Neoplasm in Korea Yoojoo Lim, Jeong-Ok Lee and Soo-Mee Bang Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Korea. Address for Correspondence: Soo-Mee Bang, MD. […]
Scientists have devised a way to destroy blood stem cells in mice without using chemotherapy or radiotherapy, both of which have toxic side effects. Blood stem cell transplantation, widely known as bone marrow transplantation, is a powerful technique that potentially can provide a lifelong cure for a variety of diseases. But the procedure is so […]
Conclusions: MPN patients are understudied and there are currently no studies that have explored the effects of physical activity on sympton burden and QoL in these patients. There is some evidence demonstrating the efficacy of physical activity for improving a variety of outcomes in specific hematological cancer subtypes. Because of preliminary evidence suggesting a positive […]
T cell Therapy shows promise fighting Blood Cancers Riddell’s preliminary findings on the success of T cell therapy to cure previously terminal cases of cancer made a stir at an annual meeting of the American Association for the Advancement of Science in Washington, D.C. on Sunday because of his eye-popping results: 93 percent of the […]
This video is outstanding, well worth watching! Dr Silver and Dr Gisslinger in Europe have been using interferon successfully for 30 years. It would be my first medication of choice in the fight against PV. I have been on Pegasys for over 2 years, so I speak from personal experience.As Dr Silver notes the combo, […]
Learning about a cancer diagnosis can be an incredibly overwhelming experience, but it’s what you do afterwards that can make all the difference for the road ahead. Learning about your condition, staying engaged in day-to-day life, and connecting with others are a few ways you can begin to cope with your diagnosis. Getting the Facts […]
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