Understanding the JAK2 Mutation

Published by mpncancer at August 30, 2016

THE STORY OF JAK2

Four teams race to find the mysterious cause of a group of blood cancers.

JAK2 MUTATIONS AT A GLANCE

Involved in: blood cancers and disorders including polycythemia vera, primary myelofibrosis, thrombocythemia, leukemia.

Testing requires: a blood draw. Bone marrow samples occasionally used.

Prognosis: Patients with a JAK2 mutation have a lower survival rate and higher rate of blood clots when compared to patients with a CALR mutation.

Treatment: Ruxolitinib may improve quality of life in patients with a JAK2 mutation.

This Gene is also known as: JTK10, THCYT3

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