MPN patients are understudied and there are currently no studies that have explored the effects of physical activity on sympton burden and QoL in these patients. There is some evidence demonstrating the efficacy of physical activity for improving a variety of outcomes in specific hematological cancer subtypes. Because of preliminary evidence suggesting a positive impact of physical activity on other hematological cancer patient outcomes, exploratory research with the MPN patient population should be considered to evaluate the potential impact of physical activity on MPN-associated symptoms and reduced QoL (quality of life).
However, it should be recognized that the etiology and treatment of MPNs is unique when compared with other hematological cancers, and therefore, the findings discussed in this review should not be interpreted to suggest that physical activity will yield similar outcomes in the MPN population. Research in this area is highly warranted.