This video is outstanding, well worth watching! Dr Silver and Dr Gisslinger in Europe have been using interferon successfully for 30 years. It would be my first medication of choice in the fight against PV. I have been on Pegasys for over 2 years, so I speak from personal experience.
As Dr Silver notes the combo, Pegasys with Jakafi (Ruxolitinib) may pack an even more potent punch against the disease. A presentation at ASH 2015 confirmed this as a “leading edge treatment” for some patients.