February 22, 2018

How MPN Blood Cancers outsmart the Immune System

AMERICAN ASSOCIATION FOR THE ADVANCEMENT OF SCIENCE Researchers have discovered how some of the blood cancers known as myeloproliferative neoplasms (MPNs) evade the immune system.  Their […]
February 1, 2018
clinical trial in myelofibrosis

Imago BioSciences gets FDA Approval of IND Application for Treatment of Myelofibrosis, IMG-7289 in Clinical Trials

Imago BioSciences, a clinical-stage pharmaceutical company developing novel therapies for hematological and inflammatory diseases, announced that the U.S. Food and Drug Administration (FDA) has accepted their […]
January 8, 2018
Celgene MPN drug Fedratinib

Celgene Acquires Impact Biomedicines, Adding Myeloproliferative Neoplasm Drug Fedratinib to Its Pipeline

Celgene Corporation (NASDAQ:CELG) and Impact Biomedicines today announced the signing of a definitive agreement in which Celgene will acquire Impact Biomedicines, which is developing fedratinib for […]
December 27, 2017
Dr Mascarenhas presenting at ASH 2017 on Nutlin

ASH 2017 Nutlin Antagonist Shows Activity in Polycythemia Vera

The investigational Nutlin family antagonist idasanutlin demonstrated significant activity and was well tolerated after multiple cycles of exposure in patients with refractory polycythemia vera (PV). Data […]
December 1, 2017

What is an MPN Specialist?

One Simple Criteria If your doc has never been to the ASH (American Society of Hematology) conference, the largest hematology convention in the world and never […]
June 29, 2017
Pegasys Jakafi combo for MPNs

Minimal Residual Disease or Cure in MPNs? Rationales and perspectives on Combo Therapy with Interferon-alpha2 and Ruxolitinib

This abstract is provided by Mads Emil Bjorn & Hans Carl Hasselbalch – Department of Hematology, Region Zealand, Roskilde, Denmark Abstract Introduction: The therapeutic landscape of […]
June 15, 2017
Dr Ruben Mesa

Dr Ruben Mesa, MPN Specialist named new director of University Texas Health Care Cancer Center in San Antonio

UT (University of Texas) San Antonio makes Dr. Ruben Mesa head of their Cancer Center Dr Ruben Mesa, one of the leading MPN Specialist in the […]
June 5, 2017
Immunofluorescence of single human cell stained grown in tissue culture, stained with multiple antibodies and visualized via confocal microscopy

A New Therapeutic Target for Myelofibrosis is cause for Gli

Abstract Myeloproliferative neoplasm cells recruit Gli1 positive mesenchymal stromal cells to transdifferentiate into fibrosis-causing myofibroblasts, a process that can be inhibited by a Gli inhibitor. Bone […]
April 28, 2017
understanding polycythemia vera

Understanding Polycythemia Vera

Understanding Polycythemia Vera (PV), A Rare Blood Cancer Behind the Mystery, Polycythemia Vera Every year, millions of patients, families and caregivers are impacted by cancer in […]
January 29, 2017
ruxolitinib and pegasys for treating MPNs

Dr Mesa and Dr Mikhael Discuss Latest MPN Research 2017

A Solid Summary on the Latest MPN Research in 2017 Drs. Joseph R. Mikhael and Ruben A. Mesa analyze and discuss pertinent clinical studies and late […]
January 2, 2017

Dying for Answers – Radiation Link to Myeloproliferative Neoplasms

Long Term Exposure to Radiation puts you at higher risk for MPN The Savannah River Site is on a list of qualified places for Special Exposure […]
December 21, 2016
MPN survey ET

Survey Seeking Essential Thrombocythemia Patients to Share Their Experiences

A survey is being conducted to learn more about the most common symptoms experienced by ET patients, and how these symptoms affect the lives of patients.  […]
October 18, 2016

Is a Cure for Blood Cancer Around the Corner?

New Leukemia Research in Phase I/IIa Clinical Trial Biosight, an Israeli pharmaceutical development company that is working on a cure for leukemia, this week closed an […]
September 21, 2016
hearing loss in PV

Study Identifies Factors Associated With Hearing Loss in Polycythemia Vera

“Researchers found that the mean hemoglobin and hematocrit levels of the polycythemia vera group were 16.7 g/dL and 50.4%, respectively, vs 13.4 g/dL and 40.3% in […]
September 20, 2016
ropeginterferon

Ropeginterferon alfa-2b, a novel IFNα-2b, induces high response rates with low toxicity in patients with polycythemia vera

Key points The novel IFNα-2b AOP2014 administered once every two weeks (or once a month) has low toxicity and induces high and sustained response rates in […]
August 30, 2016
Understanding the JAK2 mutation

Understanding the JAK2 Mutation

THE STORY OF JAK2 Four teams race to find the mysterious cause of a group of blood cancers. Click the link below for the complete article…
August 28, 2016
Frequency of MPN in Korea

Incidence, Survival and Prevalence Statistics of Classical Myeloproliferative Neoplasm in Korea

J Korean Med Sci. 2016 Oct;31(10):1579-1585. English. Published online Jul 22, 2016.  http://dx.doi.org/10.3346/jkms.2016.31.10.1579 © 2016 The Korean Academy of Medical Sciences. Incidence, Survival and Prevalence Statistics of […]
August 17, 2016
CRISPR being studied for cancer treatment

Scientists are going to use CRISPR on humans next month to try and cure cancer

Scientists in China are about to become the first to use the game-changing gene-editing technology Crispr-Cas9 on humans. Last week, Nature reported that researchers at Sichuan […]
August 16, 2016

Bone Marrow transplant without using chemo – Scientists create a safer way

Scientists have devised a way to destroy blood stem cells in mice without using chemotherapy or radiotherapy, both of which have toxic side effects. Blood stem […]
August 15, 2016
physical activity beneficial for MPNs

Physical Activity a Nonpharmacological Approach in Symptom Management in Myeloproliferative Neoplasms

Conclusions: MPN patients are understudied and there are currently no studies that have explored the effects of physical activity on sympton burden and QoL in these […]
August 13, 2016
T cells attacking blood cancer

New Treatment for Cancer may provide Hope to Incurable Patients

T cell Therapy shows promise fighting Blood Cancers Riddell’s preliminary findings on the success of T cell therapy to cure previously terminal cases of cancer made […]
August 5, 2016
hematocrit in PV, Dr Silver explains

Current Treatment Developments in Polycythemia Vera

This video is outstanding, well worth watching! Dr Silver and Dr Gisslinger in Europe have been using interferon successfully for 30 years.  It would be my […]
April 1, 2016

4 Tips for Coping with a Cancer Diagnosis

Learning about a cancer diagnosis can be an incredibly overwhelming experience, but it’s what you do afterwards that can make all the difference for the road […]