Join our newsletter

Donate to MPN-CC

Menu

myelofibrosis

clinical-trials-in-MPNs

Imago BioSciences gets FDA Approval of IND Application for Treatment of Myelofibrosis, IMG-7289 in Clinical Trials

Imago BioSciences, a clinical-stage pharmaceutical company developing novel therapies for hematological and inflammatory diseases, announced that the U.S. Food and Drug Administration (FDA) has accepted their Investigational New Drug (IND) application providing clearance to proceed with the clinical development of IMG-7289 in the U.S. The IND supports the company’s ongoing Phase 1/2 clinical trial of […]

Read More
download

Celgene Acquires Impact Biomedicines, Adding Myeloproliferative Neoplasm Drug Fedratinib to Its Pipeline

Celgene Corporation (NASDAQ:CELG) and Impact Biomedicines today announced the signing of a definitive agreement in which Celgene will acquire Impact Biomedicines, which is developing fedratinib for myelofibrosis and polycythemia vera.  Under the terms of the agreement, Celgene will pay approximately $1.1 billion upfront and up to $1.25 billion in contingent payments based on regulatory approval […]

Read More
single-human-cell-300x300

A New Therapeutic Target for Myelofibrosis is cause for Gli

Abstract Myeloproliferative neoplasm cells recruit Gli1 positive mesenchymal stromal cells to transdifferentiate into fibrosis-causing myofibroblasts, a process that can be inhibited by a Gli inhibitor. Bone marrow fibrosis (BMF), characterized by deposition of reticulin and collagen fibers in the marrow, is a hallmark of primary myelofibrosis (PMF) and other myeloproliferative neoplasms (MPNs).  PMF is characterized […]

Read More
Back To Top
error: Content is protected !!

MPN CANCER CONNECTION

is a 501 (c) (3) non-profit public charity, our tax ID number is 47-4839850.

Privacy Policy

Copyright © 2024 MPN Cancer Connection,
All Rights Reserved

JOIN OUR NEWSLETTER

Site by: Kaleidoscopic